Microbial butanol tolerance: mediated by toxicity or by phase equilibrium?

It is conventionally assumed that the achievable concentration of a bio-alcohol molecule by fermentation is limited by the toxicity of that molecule to the micro-organisms producing it. In the case of ethanol, for example, extremely high titers... continue reading

A combinatorial approach towards treating cancer through Cisplatin

Cisplatin is an effective chemotherapeutic drug against a vast variety of cancers. It is a cytotoxic drug that kills cancer cells by forming DNA adducts, thereby damaging the DNA leading to apoptosis. However, the clinical use of cisplatin is... continue reading

A service to assess the quality of documentation of open source software

Could one build a service that checks the completeness and quality of documentation of an open source repository?

Potentially a group could build up a set of repositories with documentation ratings, which could then be used to train a ML/DL... continue reading

Effects of temperature on alcohol tolerance of microbes

It has been established that dissolution of membrane lipids plays a role in the toxicity of ethanol and butanol to micro-organisms; a matter of particular importance for the production of bio-alcohol fuels using fermentation by microbial activity.... continue reading

Bayesian verdicts

Why do juries emit binary verdicts, i.e. guilty or not guilty? Why not allow each juror to emit a "Bayesian vote" reflecting his/her subjective degree of belief in the probability of the defendant’s guilt? Under this alternative method of Bayesian... continue reading

Antibiotics indicating a link between migraines and gut bacteria

Recent research has found links between the composition of gut bacteria and whether a person suffers from migraines. Since [antibiotics influence gut... continue reading

FearOmone: A cat pheromone based Bio-synthetic deterrent to minimize post-harvest losses caused by rat manifestation.

In India, post-harvest losses amount to 16 million metric tons of food grains each year (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296677/). Improper storage and transport is the main problem to be addressed since it contributes to more than... continue reading

Phylogenetic tree representation in n-dimensional space

Traditional phylogenetic trees are represented as bifurcating trees, where the leaf nodes represent taxa and the internal nodes represent common ancestors. Bifurcating trees offer advantages of interpreting common ancestors as well as being widely... continue reading

Use of waste plastic as a reducing agent for iron ore

China's recent announcement that they will cease to accept large quantities of waste plastic has brought a growing crisis into sharp focus; global capacity for waste plastic handling is being rapidly outstripped by production. The clear solution... continue reading

Orthogonal versus redundant data in education

Our university was recently hit by malware. It took weeks to restore most data, some lost completely. All backups were affected making a simple restore ineffectual. Why take this redundant approach in data safety? Consider flight data recorders:... continue reading


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