From Publication to Impact: When publication isn’t enough for patients, measure what matters.

The ultimate beneficiary of a biomedical journal article should be the patient. To realize this benefit, a publication must provide both the rational evidence plus a reason to act on the part of a healthcare professional. Sponsors of clinical... continue reading

Axiology: is a learning intervention worth the effort?

Many medical education studies pursue a measurement approach to demonstrate the efficacy of a learning intervention. Researchers, steeped in the belief system that positions randomized controlled trials as the ultimate form of inquiry, try to... continue reading

An algorithm to end gerrymandering

U.S. House of Representative districts are bounded by centuries-old state borders, and redrawn by state legislatures. This has led to constitutional problems, and overcoming the problem of gerrymandering has not gone away. I propose a... continue reading

On the Impossibility of Aggregating Individual Cloud Accretion Rates

The rate of accretion onto the Milky Way (MW) by an individual cloud (or satellite) can be written as dM/dt = M v / R, where M is the cloud mass, v the cloud velocity toward the MW, and R is the distance from the cloud to the MW. Over the time t =... continue reading

Apple and orange: comparing patient safety, health data and the airline industry

Over the decades, the airline industry which was already very safe, has made further strides to improve safety. The current trend in patient safety and simulation conferences is to repeatedly draw parallel conclusions, decrying those in healthcare... continue reading

Beyond Gaia: A Deep-Space Astrometric Mission To Obtain ~1% Parallax Distances at 10 kiloparsecs

The Gaia space telescope is currently measuring parallax distances for Galactic stars with ~1% precision out to ~1kpc. This will be a revolutionary data set, but order-of-magnitude improvements are possible with... continue reading

Autism microglia research

I am forming a group to submit a proposal to an NIH GRANT regarding Autism. The GRANT is R0. The deadline is 09/2019. The Main idea is state of microglia on autism. The theories behind area 2: white matter changes based on previous studies and... continue reading

Epidemiology of musculoskeletal disorders and injuries among patients in a tertiary care public hospital.

Musculoskeletal disorders are a major cause of morbidity, influence health and quality of life and impose an enormous burden on our healthcare system.

Injury is now a leading cause of mortality and morbidity worldwide. Injuries on roads, at... continue reading

Novel method to isolate and identify specific RNA/DNA binding proteins

Owing to their role in establishing cell asymmetry and their role in pathological conditions such as neurodegenerative diseases, it is very important to focus on eukaryotic RNA-binding proteins(RBPs) binding to a specific transcript(s). Although... continue reading

Human oral microbiome crisis at the end of 18th c.?

Scholars have recently shown a clear increase in the frequency of caries and tooth loss for humans after the end of the 18th c. [1] For the authors, changes in nutrition (more sugar) and dental health (possibly higher frequency of tooth... continue reading

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