Co-immunoprecipitation (co-IP) is considered the gold standard in vitro technique for characterising protein-protein interactions. However, the technique is limited by the inability to differentiate direct/indirect interactions of proteins. This... continue reading
One measure of the performance of a diagnostic test is the proportion of patients the test stratifies as likely not to have the condition (ruled-out:RO) or to have the condition (ruled-in:RI). This proportion depends on the prevalence of the... continue reading
MAOI and St John's Wort treatments for OCD may have a similar radical-based mechanism. Six years' unrelieved total compulsive thinking was cured by the MAOI Phenelzine, with also a role for radical-releasing phenols which enter the CNS very little... continue reading
A Pareidolic Response to Environmental Stimuli occurs when it is triggered by a certain richly textured surface or object . This human trait is a result of a survival mechanism, where the environment is quickly scanned for potential threats. A... continue reading
Species Distribution Models are commonly used to predict species habitat suitability. The data needed to build such a model usually consist of a range of environmental variables together with a target variable - the species occurrence itself... continue reading
It is conventionally assumed that the achievable concentration of a bio-alcohol molecule by fermentation is limited by the toxicity of that molecule to the micro-organisms producing it. In the case of ethanol, for example, extremely high titers... continue reading
Cisplatin is an effective chemotherapeutic drug against a vast variety of cancers. It is a cytotoxic drug that kills cancer cells by forming DNA adducts, thereby damaging the DNA leading to apoptosis. However, the clinical use of cisplatin is... continue reading
Could one build a service that checks the completeness and quality of documentation of an open source repository?
Potentially a group could build up a set of repositories with documentation ratings, which could then be used to train a ML/DL... continue reading
It has been established that dissolution of membrane lipids plays a role in the toxicity of ethanol and butanol to micro-organisms; a matter of particular importance for the production of bio-alcohol fuels using fermentation by microbial activity.... continue reading
Why do juries emit binary verdicts, i.e. guilty or not guilty? Why not allow each juror to emit a "Bayesian vote" reflecting his/her subjective degree of belief in the probability of the defendant’s guilt? Under this alternative method of Bayesian... continue reading
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