A combinatorial approach towards treating cancer through Cisplatin

Cisplatin is an effective chemotherapeutic drug against a vast variety of cancers. It is a cytotoxic drug that kills cancer cells by forming DNA adducts, thereby damaging the DNA leading to apoptosis. However, the clinical use of cisplatin is limited by severe side effects in healthy tissues wit...

By Ashwin K. Jainarayanan, Ankush Sharma

Systems analysis of cancer progression

It is well-known that the stage of the cancer at diagnosis is significantly correlated with the survival odds of the patient, and the chances of survival fall off rapidly with the progression of cancer. Despite this, few efforts address the mechanisms of progression of the disease. Here we sugge...

By Ashok Palaniappan