HIV Variation Driven By Somatic Hypermutation in Immunoglobulin Variable Genes

Here is an explanation for HIV variation:
• HIV-1 infects many white cells - but particularly activated B cells in the early phase of infection setting up productive provirus in a significant fraction.
• During somatic hypermutation of the... continue reading

Acknowledgment re ‘The mil: 1/1023 of an equal-tempered semitone’

Eight of the twelve intervals mentioned in the above Brief Idea (10.5281/zenodo.16212) were given in 12276ths of an octave, explicitly or implicitly, by Erv Wilson in 1995; see the last two... continue reading

The mil: 1/1023 of an equal-tempered semitone

In musical temperament, intervals are usually stated in cents, i.e. hundredths of a 12-EDO semitone. A more convenient unit would be 1/12276 of an octave, i.e. 1/1023 of a 12-EDO semitone. I call this a mil because it... continue reading

Forensic facial reconstruction or facial approximation?

Our body changes from one day to the other, from fat to thin, from young to old, without any significant facial bone surface modification. The same from upright to horizontal position, with gravitational deformations of sub-cutaneous fatty and... continue reading

The social media spontaneous order is a ‘constellaxy’

Social media is a spontaneous order. It is distinct from others because of its systemic resource—attention—and unique feedback mechanisms—social media analytics[1]. Attention... continue reading

The spontaneous order of social media

Social media is a spontaneous order. Or, rather, various social orders cultivated on social media platforms—patterns of interaction, virtual communities, co-creation and user-generated content—constitute their own spontaneous orders. Social media... continue reading

haze monitor with MPPSK satellite signal

The haze monitoring technique by MPPSK satellite signal is the new idea. MPPSK satellite signal delay is received by satellite ground-based receivers whose positions are set. Troposphere delay is used fordistribution calculation . Raw data is... continue reading

A Novel Approach to Potentially Improve SNR in Gravitational Wave Detection

Gravitational wave detection aims to measure extremely weak vibration signals that are deeply drowned in noise. Therefore, improving Signal to Noise Ratio (SNR) is crucial for such detection systems including laser interferometer gravitational... continue reading

Suggestion: Is a change in perception necessary to modulate cognitive conflict?

It has been suggested that when in a highly focused state, some individuals can better utilise attentional resources allowing them to ignore stimuli which may be distracting. Further, it has been postulated that hypnosis is nessesary in... continue reading

Marine sponge-associated bacteria: A new source for Polyhydroxyalkanoates (PHAs)

Polyhydroxyalkanoates (PHAs) possess a wide range of well-established industrial applications and being considered as alternate for fossil-fuel derived/synthetic plastics. Major research efforts are currently focusing on increasing the ability to... continue reading

Welcome

This is the Journal of Brief Ideas - citable ideas in fewer than 200 words.

Before you can create a new idea, you'll need to log in using the link above. You also can't vote on existing ideas without signing in too.

Voting

Click on the icon to vote on an idea. You can't vote on your own ideas.