Effect of PH on Copper hypertolarence: How does the Copper exporters of Staphylococcus aureus are maintaining its functionality within low PH of Phagosome ?

We know that, when any bacterium entered into our body as per the innate immunity phagocytic cells majorly macrophages activated and use copper into phagosome to kill the phagocytized bacterium. Unfortunately most of the bacterium is capable to... continue reading

Delivery of Grocery items before demand

To delivery of the items before demand, it is important to know the monthly demands of the various families. so collect the information like size of family, festival celebration, possibilities of guest arrival, daily and monthly demand of various... continue reading

Backward stepwise elimination: A model-based method for nonlinear dimension reduction

In multidimensional data modeling, dimension reduction is not intuitive. Forward feature selection is usually deceptive. That is, a strongly related feature may have a small correlation coefficient (near zero) to the objective, especially when the... continue reading


As mentioned in articles in NPBR.1. and JBI.2., the crucial stage in MAOI and St John' s Wort OCD cures I have repeatedly found to be strong TRPA1 receptor activation by radicals, resulting in gut serotonin and CCK release. Matsuo et al.3. have... continue reading

Neutrophils reduction by inducing autophagy may improve cancer treatment?

Neutrophils are the key players of innate immune system that is well known to us. The information’s, which excite the new age researchers, is that the neutrophils may also be key players in cancer initiation and progression by several aspects. A... continue reading

Carnot temperature and microwave cooking

Industrial chemical reactors are commonly understood as analogous to heat engines; chemical processes frequently require both heat (increase in energy) and work (decrease in entropy) to operate. Just like in a heat engine, work can be supplied... continue reading

Clarifying Heraclitus' criticism of polymathy as a bad craft

In fragment XXV (Khan, 1979), Heraclitus writes that polymathy is bad craft (kakotechnie). However, in that extract he is referring to the “pilling up” of learnings without the application of rigor and without good guiding principles.
... continue reading

Benefits of publishing power analysis reports

I propose that a lack of opportunities for publishing "power analysis reports" may be a gap worth addressing in scientific publishing. Scientific journals offering a "power analysis report" article type could have a number of benefits:

1 - It... continue reading

Exhaled Nitric Oxide test for COVID-19 severity screening

Exhaled Nitric Oxide (FeNO) testing is a widely-used diagnostic tool in the treatment of asthma, where it is used to estimate the extent of inflammation in the airways. Airway inflammation also plays a significant role in the disease progression... continue reading

Measuring economic parameters of games

Players need to recognize and follow each game’s rules in order to participate ([Squire,... continue reading


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