DNA is a (geo)political weapon
The use of DNA (both modern and ancient: aDNA) for purposes of genetic traceability, ethnic filiation, migration of populations, etc. is currently experiencing exponential growth. These studies are (it is hoped) initially motivated by scientific... continue reading
From Publication to Impact: When publication isn’t enough for patients, measure what matters.
The ultimate beneficiary of a biomedical journal article should be the patient. To realize this benefit, a publication must provide both the rational evidence plus a reason to act on the part of a healthcare professional. Sponsors of clinical... continue reading
Axiology: is a learning intervention worth the effort?
Many medical education studies pursue a measurement approach to demonstrate the efficacy of a learning intervention. Researchers, steeped in the belief system that positions randomized controlled trials as the ultimate form of inquiry, try to... continue reading
An algorithm to end gerrymandering
U.S. House of Representative districts are bounded by centuries-old state borders, and redrawn by state legislatures. This has led to constitutional problems, and overcoming the problem of gerrymandering has not gone away. I propose a... continue reading
On the Impossibility of Aggregating Individual Cloud Accretion Rates
The rate of accretion onto the Milky Way (MW) by an individual cloud (or satellite) can be written as dM/dt = M v / R, where M is the cloud mass, v the cloud velocity toward the MW, and R is the distance from the cloud to the MW. Over the time t =... continue reading
Apple and orange: comparing patient safety, health data and the airline industry
Over the decades, the airline industry which was already very safe, has made further strides to improve safety. The current trend in patient safety and simulation conferences is to repeatedly draw parallel conclusions, decrying those in healthcare... continue reading
Beyond Gaia: A Deep-Space Astrometric Mission To Obtain ~1% Parallax Distances at 10 kiloparsecs
The Gaia space telescope is currently measuring parallax distances for Galactic stars with ~1% precision out to ~1kpc. This will be a revolutionary data set, but order-of-magnitude improvements are possible with... continue reading
I am forming a group to submit a proposal to an NIH GRANT regarding Autism. The GRANT is R0. The deadline is 09/2019. The Main idea is state of microglia on autism. The theories behind area 2: white matter changes based on previous studies and... continue reading
Musculoskeletal disorders are a major cause of morbidity, influence health and quality of life and impose an enormous burden on our healthcare system.
Injury is now a leading cause of mortality and morbidity worldwide. Injuries on roads, at... continue reading
Novel method to isolate and identify specific RNA/DNA binding proteins
Owing to their role in establishing cell asymmetry and their role in pathological conditions such as neurodegenerative diseases, it is very important to focus on eukaryotic RNA-binding proteins(RBPs) binding to a specific transcript(s). Although... continue reading
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