[{"id":777,"title":"Excessive sitting time as predictor of COVID-19 severity","sha":"17392d36e3cbafce1ae1f457b632202b","user_id":null,"state":"published","body":"A large body of recent research has identified that excessive time spent sitting down is a major risk factor for mortality from all causes and that it directly contributes to a range of health issues prevalent in first-world countries. Many of those health issues have also been identified as significant co-morbidities contributing to mortality in COVID-19 patients. One can infer that in aggregate, amount of time spent sitting will be a good predictor of COVID-19 mortality. This would be expected even in the absence of diagnosed co-morbidities because multiple of those risk factors are likely to be present at sub-clinical levels in individuals who sit excessively. It is further hypothesized that the direct contribution of sitting to conditions conducive to blood clots will have a synergistic effect with COVID-19’s mechanisms for coagulopathy, resulting in clot formation in excess of what would be expected by adding those two risk contributions.","created_at":"2020-08-22T10:09:02.930Z","updated_at":"2020-08-23T06:00:28.510Z","zenodo_id":3996048,"doi":"https://doi.org/10.5281/zenodo.3996048","subject":null,"tags":["covid-19; medicine; risk"],"vote_count":0,"view_count":1,"score":0.1,"deleted":false,"muted":false,"tweeted":true,"attachment_file_name":null,"attachment_content_type":null,"attachment_file_size":null,"attachment_updated_at":null}]