[{"id":462,"title":"OCD, ST JOHN'S WORT AND IRON.","sha":"829e23a13f3a464704c08167f974fab8","user_id":null,"state":"published","body":"MAOI and St John's Wort treatments for OCD may have a similar radical-based mechanism. Six years' unrelieved total compulsive thinking was cured by the MAOI Phenelzine, with also a role for radical-releasing phenols which enter the CNS very little .1. (Journal of Brief Ideas article \"Oxidative stress, MAOIs and OCD\"). Side-effects lead to a search for alternatives. St John's Wort extract proved ineffectual (at 5 x 333 mg whole herb equivalent per day), but cure was greatly improved when ferrous fumarate was added to St John's Wort (at 2 x 14 mg per day). This improved cure, just as on the MAOI, did not happen until after several weeks, but followed 24 - 48 hours after the advent of peripheral serotonin release patterns. This suggests that the enabling of radical-based releasing of serotonin is a crucial first stage, as on MAOIs, as excess iron ions are known to increase the radical effects behind gut serotonin release by cisplatin and pyrogallol, for example. .2. \r\n.1. Neurology,Psychiatry and Brain Research 5(4):181, 8(4):185, 10(4):149.\r\n.2. European Journal of Pharmacology: Environmental Toxicology and Pharmacology.(1993) 248:329-331.  ","created_at":"2018-06-23T19:39:23.672Z","updated_at":"2018-07-06T17:11:57.596Z","zenodo_id":1297179,"doi":"https://doi.org/10.5281/zenodo.1297179","subject":null,"tags":["ocd","iron"],"vote_count":1,"view_count":1,"score":1.1,"deleted":false,"muted":false,"tweeted":false,"attachment_file_name":null,"attachment_content_type":null,"attachment_file_size":null,"attachment_updated_at":null},{"id":226,"title":"Isolation and characterisation of novel methanogens from corroded oil/gas pipes","sha":"b6dbad8c0ee8b8e7fc02b4644795df10","user_id":null,"state":"published","body":"Methanogens are microorganisms which produces methane as a major product of their energy metabolism in anaerobic conditions. Methanogens are very common in wetlands and produces marsh gas. They are recently discovered to directly feed on electrons from Fe(0). These microorganism respires carbon dioxide and produces methane. However, it is unknown that these methanogens receive electrons from Fe(0). They also helps in corrosion which in a way is directly lethal to humans. \r\nThe implications are remarkable, not only for the prevention of corrosion, but also for extracellular electron transfer processes relevant for many applications such as anaerobic digestion and microbial electrosynthesis for production of valuable chemicals.\r\nHighly corrosive methanogenic strains are not yet discovered but can be isolated and characterised from corroded oil/gas pipes from all over the world using molecular techniques and microbiological experiments along with its characterisation using bio-informatic tools. Initiation of corrosion and its colonisation can be a good subject to work with. The discovery of the promotion of electron uptake from metallic iron can be worthy for human health. Development of new tools against corrosion in corroded oil/gas pipes can be a nobel winning work which may help human health by discouraging microbial attachment and electron retrieval.\r\n","created_at":"2015-09-16T18:58:44.680Z","updated_at":"2015-09-17T07:12:12.108Z","zenodo_id":61237,"doi":"http://dx.doi.org/10.5281/zenodo.31055","subject":null,"tags":["metanogens","isolation","characterisation","corrosion","iron","electrosynthesis","applications","health"],"vote_count":1,"view_count":1,"score":1.1,"deleted":false,"muted":false,"tweeted":false,"attachment_file_name":null,"attachment_content_type":null,"attachment_file_size":null,"attachment_updated_at":null},{"id":436,"title":"Use of waste plastic as a reducing agent for iron ore","sha":"a68934a13a3acecaf3a25b551b5c7332","user_id":null,"state":"published","body":"China's recent announcement that they will cease to accept large quantities of waste plastic has brought a growing crisis into sharp focus; global capacity for waste plastic handling is being rapidly outstripped by production. The clear solution is to find ways of profitably utilizing waste plastic, preferably involving total chemical conversion to non-persistent substances.\r\nOne possibility that has been previously neglected is that of using plastic instead of coal as a reducing agent for iron ore. The first criterion for a reducing agent is the chemical capacity to take up the excess oxygen atoms contained in hematite and magnetite. Polyethylene polymer has an effective chemical formula of (C2H4)n, and both Carbon and Hydrogen can be bonded to oxygen to form a range of stable compounds. The other criterion for a viable reducing agent is possessing sufficient chemical energy to drive the endothermic reduction of iron. Polyethylene has an enthalpy of formation of -(94.26n)kJ/mol and a Gibbs free energy of formation of -(36.44n)kJ/mol, giving it sufficient energy density for this purpose. In principle, therefore, it is perfectly viable to use waste plastic instead of coal for the reduction of iron ore.","created_at":"2018-01-18T09:36:12.903Z","updated_at":"2018-01-30T06:01:09.762Z","zenodo_id":1162364,"doi":"https://doi.org/10.5281/zenodo.1162364","subject":null,"tags":["emissions","plastic","recycling","iron"],"vote_count":0,"view_count":1,"score":0.1,"deleted":false,"muted":false,"tweeted":true,"attachment_file_name":null,"attachment_content_type":null,"attachment_file_size":null,"attachment_updated_at":null}]