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Ideas tagged with microvesicles

Self-propagating mRNAs, a novel gene therapy method and delivery vector

Self-propagating mRNAs could be engineered to replicate itself and exit cells via microvesicles. They could be used in gene therapy to express target genes without disrupting the genomic DNA. These mRNAs have multiple open reading frames (ORFs). Some ORFs encode the non-structural proteins (nsp)...

By Yancheng Li