[{"id":78,"title":"Cancer cell nuclear expulsion: a possible mechanism of survival, and metastasis capability. ","sha":"b566367fae06afe6914bece416ea75cd","user_id":283,"state":"published","body":"A very interesting and novel experiment was carried out by Florina Bojin et al [Wiley](http://onlinelibrary.wiley.com/doi/10.1111/jcmm.12271/abstract). Constructing on this published work, I propose a novel survival mechanism of the cancer cell, and a new metastasis mechanism. Giving that cancer cells are known for their survival capabilities, could a nuclear expulsion -produced by stress, either biochemical, mechanical or nutritional- be used as survival mechanism, and, or a seeding action? The questions are many, but the answers could bring a new understanding of what exactly constitutes a cell or could a nucleus of of a cell -cancer cell- survive without its host cell? I propose a further investigation of the possibility that a cancer cell nucleus could be a seeding apparatus for metastases. Would a nucleus be able to ''high-jack''  another cell -if the nucleus survives the expulsion-? Is there an immune response to an ejected nucleus? I think the first steps are to confirm the existence of nuclear expulsion In Vivo, the viability of the ejected nuclei, and the possibility of ''nuclear cellular high-jacking''.\r\nThank you.     ","created_at":"2015-02-20T21:35:36.809Z","updated_at":"2015-02-26T11:52:06.861Z","zenodo_id":23227,"doi":"http://dx.doi.org/10.5281/zenodo.15562","subject":null,"tags":["science","cancer","molecularbiology","mechanism","cellular"],"vote_count":3,"view_count":1,"score":3.1,"deleted":false,"muted":false,"tweeted":false,"attachment_file_name":null,"attachment_content_type":null,"attachment_file_size":null,"attachment_updated_at":null},{"id":23,"title":"Reanimation of Australian Megafauna, Extinct Species and New Zealand Moas","sha":"5d87b73cfbbd112200914f3638f5f3af","user_id":45,"state":"published","body":"After the arrival of the first humans, Indigenous Australians, to the island continent, the previous megafauna became extinct.  As many samples are still extant, deriving DNA samples or fragments and reverse engineering, through multiple generations could allow us to recreate these fauna, or at the very least, increase our understanding of development, evolution and reproductive technology. It will also increase our technical know how for the development of useful synthetic organisms","created_at":"2015-02-11T01:57:22.473Z","updated_at":"2015-05-27T20:43:01.766Z","zenodo_id":21947,"doi":"http://dx.doi.org/10.5281/zenodo.15013","subject":null,"tags":["synthetic","biology","genetics","reanimation","molecularbiology","extinction"],"vote_count":2,"view_count":1,"score":2.1,"deleted":false,"muted":false,"tweeted":false,"attachment_file_name":null,"attachment_content_type":null,"attachment_file_size":null,"attachment_updated_at":null}]