[{"id":727,"title":"Stem Cell Based Approach for Control of Invasive Fish Species","sha":"247c60033e4cd7ab4e132cf3d8ad228d","user_id":null,"state":"published","body":"Germ cell (GC) transplantation (GCT) is widely used for generating surrogate gametes from commercially important fishes that are difficult to breed in confinement and propagation of endangered populations. Here is an innovative application of GCT for control of invasive fish population those pose havoc to the native ecosystem. The donor GCs from commercially important native fish species will be isolated and transplanted through the genital papilla into the gonads of recipient invasive fish species that should be prior depleted of endogenous GCs by cytotoxic drug and high water temperature treatments. Few months after GCT, the donor GCs will proliferate and differentiate into functional donor-origin gametes. The natural spawning between males and females of invasive fish species will generate commercially important native fish species progeny and there will not be any progeny of invasive fish species (Figure 1). The simple yet viable idea of GCT present here could be useful for ecosystem management especially for control of invasive fish species those causes huge economic losses worldwide. ","created_at":"2020-04-27T14:01:38.167Z","updated_at":"2020-04-28T06:00:36.019Z","zenodo_id":3771817,"doi":"https://doi.org/10.5281/zenodo.3771817","subject":null,"tags":["stem cell","fishery resources management","invasive fish","germ cell transplantation"],"vote_count":0,"view_count":1,"score":0.1,"deleted":false,"muted":false,"tweeted":false,"attachment_file_name":"Figure_JBI.jpg","attachment_content_type":"image/jpeg","attachment_file_size":110210,"attachment_updated_at":"2020-04-27T14:01:38.115Z"},{"id":990,"title":"The Cocktail Therapy of using nanobots and mitochondrial transplantation along stem cells for salvaging dying organs of end stage failure","sha":"f870242d1bab81c7d5aa2d533970be7e","user_id":null,"state":"published","body":"The  concept is to combine all the 3 modalities of treatment which is basically injecting programmed medical nano-robots also known as nanite which is very tiny in size with dimensions in nanometers as it could perform a variety of  functions, from disposing away dead cells at a wound and helping in re-growing tissue so that it heals cleanly and quickly without leaving a nasty scar to festering wounds. \r\nThe entire process of nanotech together with mitochondrial transplantation can open new doors \u0026 bring new possibilities since collecting a patient’s healthy mitochondria from a different tissue which is tiny oval structures that provide cells with energy to function and injecting them into damaged tissue. If it works as expected, the healthy mitochondria get absorbed into damaged cells and help them heal from the inside as If these powerhouses could be transferred from one cell to another and retain their function, maybe they could be used to heal tissues with dysfunctional mitochondria. Altogether with stem cell therapy can enhance the overall treatment towards a new horizon of cure based on their advantages of plasticity, infinite amplification, and ease of genetic manipulation, stem cell therapy opens new avenues for almost all human diseases.","created_at":"2022-07-03T23:35:45.224Z","updated_at":"2022-08-07T06:00:34.433Z","zenodo_id":6970241,"doi":"https://doi.org/10.5281/zenodo.6970241","subject":null,"tags":["nanite","mitochondria","transplantation","nanotech","stem cell"],"vote_count":0,"view_count":1,"score":0.1,"deleted":false,"muted":false,"tweeted":false,"attachment_file_name":null,"attachment_content_type":null,"attachment_file_size":null,"attachment_updated_at":null}]