Trending ideas
Self-propagating mRNAs, a novel gene therapy method and delivery vector
Self-propagating mRNAs could be engineered to replicate itself and exit cells via microvesicles. They could be used in gene therapy to express target genes without disrupting the genomic DNA. These mRNAs have multiple open reading frames (ORFs).... continue reading
Proposed Definition of Polymathy and Polymathic Orientation
Polymathy is a multidimensional approach to learning and personal development that involves the pursuit, development, and application of knowledge characterized by three dimensions: breadth, depth, and integration. (1) Breadth refers to the... continue reading
Climate change is a worldwide problem felt locally in municipalities. Mitigation and adaptation climate actions are carried out by many entities [1]. Multi-level governance articulates local,... continue reading
Engine change at 80MPH: OSS projects as laboratories for participatory governance transformation
Online communities are high-throughput laboratories for governance change and innovation. Elinor Ostrom's idea of institutional diversity, that sustainable resource governance requires a diversity of governance forms and approaches, is well... continue reading
Global warming has increased due to accumulation of Carbon Dioxide, creating serious impacts on the existence of humans and their activities. The learning- teaching efficiency is also impacted by higher temperatures. The educational institutes... continue reading
Materials acceleration platforms have the potential to reduce the cost- and time-to-market of new materials from 20 million USD and 20 years to as little as 1 million USD and 1 year; however, the capital and expertise are often significant.... continue reading
Hypothesis: systemic low-grade tissue hypoxia as contributing causative mechanism for Long COVID
Silent hypoxia is one of the key clinical features of COVID-19 infection. Some of the hypothesized underlying causes of silent hypoxia, such as endothelial and micro-vascular dysfunction, and micro-clots inhibiting perfusion, would exert a... continue reading
Calculation of multi-dimensional information acquisition in space potential disintegration target
Some space debris belongs to the upper stage of the rocket, and propellant remains inside the debris, which may explode and generate more space debris. In order to identify potential disintegration targets in space, understand the remaining amount... continue reading
Spacecraft cluster cloud high-frequency optimization computing theory
The satellite-ground collaborative computing requires information transmission between the satellite and the ground, which will cause significant delay, resulting in a time from calculation to execution of more than milliseconds. In the best case,... continue reading
Develop a uniform tool to assess sanitation in urban slums
The quality of sanitation is poor in urban slums across the globe. Sanitation deprivations are greater in urban slums in developing countries, which continually experience unmanageable influxes of slum dwellers.
Governments have limited... continue reading
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