[{"id":225,"title":"Evolution in genetic terms – Is it RNA world or DNA world or is it anything else?","sha":"69b03c4db6269df0798781ef07244e59","user_id":null,"state":"published","body":"\r\nThe RNA world concept that self-replicating ribonucleic acid (RNA) molecules are keys to all current forms of life on Earth and geticists could not go further down might have missed out on how evolution has actually happened in real genetic terms. \r\n\r\nOut of all hypothesis and proposals, one that stands strong in the debate of “RNA before DNA” is \u003cb\u003e “protein synthesis can occur in the absence of DNA but not in the absence of RNA” \u003c/b\u003e. To contest this hypothesis, one should take a close look on life of an RNA molecule and their early degeneration process. \r\n\r\nEarlier RNA-protein interaction systems are highly doubtful because RNA is never a long-time informational molecule and even if they are or they used to be, many such information might got lost. Assuming this kind of unstable molecule being the early days primary replication machinery, information contents might have significantly lost and this will again raise a question on how similar or same species maintains identity?\r\n\r\nTransferring information outside of the nucleus is only required when there is a nucleus.\r\n\r\nTaken together these concepts, \u003cb\u003ewe need to revisit the origin of life in newer genetic terms.\u003c/b\u003e\r\n","created_at":"2015-09-16T17:43:27.824Z","updated_at":"2015-09-18T06:00:54.818Z","zenodo_id":61235,"doi":"http://dx.doi.org/10.5281/zenodo.31054","subject":null,"tags":["evolution","rna","dna","rna world","dna world","genetics"],"vote_count":1,"view_count":1,"score":1.1,"deleted":false,"muted":false,"tweeted":false,"attachment_file_name":null,"attachment_content_type":null,"attachment_file_size":null,"attachment_updated_at":null}]